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Can proteins be designed to perform functions that natural evolution has not supplied? The Nanda Lab develops computational tools for protein design, structure prediction, and molecular docking. Its projects include designing collagen based extracellular matrices, studying how nonnatural amino acids affect peptide stability, and investigating the relationship between protein digestion and food allergy. Designed matrices are characterized experimentally to examine how their chemical and spatial organization influences cells. The work links structural biology and molecular evolution to biomaterials and possible biomedical applications.
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Computational protein designCollagenBiomaterialsPeptide stabilityStructural biology
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