Shikha Nangia Research Group

Syracuse University

Shikha Nangia’s group models biological barriers at molecular scales to understand why some drugs cannot reach their targets. A central project examines the architecture of the blood-brain barrier and possible pathways for transporting therapeutic molecules into the brain. Multiscale computational work also covers membrane proteins, lipid and bacterial membranes, disordered proteins, drug delivery, and responsive polymers. The program connects engineering, chemistry, biophysics, and computation with experimental collaborations. Its simulations explore mechanisms and design possibilities relevant to disease research without treating modeled delivery strategies as established therapies.