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Immune cells can behave very differently even when they look similar. Navin Varadarajan’s group develops high-throughput assays to measure the functions of individual cells, including how T cells recognize and kill cancer targets. Its work connects single-cell profiling, microscopy, and protein engineering with therapeutic antibodies, autoimmune disease, and cancer immunotherapy. Published studies examine antitumor cell interactions and ways to improve engineered immune-cell therapies. The group’s approach emphasizes what cells actually do, creating a functional view that complements measurements of genes or molecular markers.
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