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An animal and its resident microbes develop in constant interaction. Karen Guillemin investigates how hosts and microbial communities shape one another in development and disease, using zebrafish and fruit flies as experimentally tractable systems. Her lab combines live imaging and genetics to study bacterial colonization, including intestinal communities and Helicobacter pylori sensing. It also examines how microbial communities assemble in hosts. These projects connect microbiology, developmental biology, and inflammation, offering a focused way to explore the mechanisms behind host-microbe relationships.
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