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An engineered tissue needs an environment that helps cells organize and develop. Papavasiliou designs synthetic hydrogel scaffolds whose stiffness, degradation, and biochemical composition can be adjusted to influence cell behavior and vascular growth. Her research includes scaffolds containing cells and material gradients for regenerating complex tissue interfaces. Other projects develop nanoparticle emulsions for targeted drug delivery and models that connect polymer structure to therapeutic diffusion. The work combines biomaterials design with tissue engineering, examining how material properties shape biological responses.
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