Omid Veiseh Research Group

Rice University

How can engineered biomaterials control host immune responses to enable long-term function of implanted therapeutic devices? The group develops implantable multi-scale devices and biomaterials for cell transplantation, localized controlled drug release, continuous sensing, and tissue regeneration. They combine nano-, micro-, and macro-scale fabrication with molecular engineering and cellular and molecular biology methods to tune geometry, porosity, mechanical stiffness, and surface chemistry of materials. Researchers apply synthetic biology and immunoengineering to build cell-based platforms for real-time and feedback-regulated production of biologics. The team develops tools to non-invasively track cellular and biomolecular activity in vivo to assess host responses and device performance.