Nan-kuei Chen Research Group

University of Arizona

How can MRI acquisition and reconstruction be improved to deliver high-resolution, artifact-free scans for challenging patients within clinical time limits? The research develops novel acquisition and reconstruction approaches, including multiplexed sensitivity encoded (MUSE) MRI, to map human brain connectivity at high spatial resolution. Projects focus on artifact characterization and correction for EPI distortions, susceptibility-induced signal loss, Nyquist and motion-induced phase errors using pulse sequence design and signal processing. Researchers combine fast image acquisition, denoising, and algorithm development to enable multi-contrast and quantitative MRI in clinically-feasible timeframes. The lab implements and validates methods through applied studies, NIH-funded projects, and collaborations on diffusion and functional MRI.