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What molecular changes accompany rare genetic diseases that damage the nervous system? The lab uses mass spectrometry to investigate neurodegenerative disorders, including genetic lysosomal storage diseases. Its research brings analytical chemistry together with biochemistry, molecular biology and human health. The department describes related research in proteomics and neurobiology, including molecular processes involved in neuronal connections, synaptic transmission and neurodegeneration. These directions connect measurements of biological molecules with questions about how nervous-system function becomes disrupted in disease.
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Mass spectrometryNeurodegenerationProteomicsLysosomal storage disease
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