Howard E. Gendelman Research Group

University of Nebraska Medical Center

Gendelman connects immune biology with new approaches to infectious and neurodegenerative disease. His laboratory investigates long-acting antiretroviral delivery, gene editing, and immune-directed strategies for protecting the brain. Research combines brain and immune-cell cultures, animal models, microscopy, proteomics, and measurements of drug delivery through immune cells. Other projects explore protective T-cell responses and delivery approaches relevant to Parkinson’s disease. The group offers an interdisciplinary research direction where pharmacology, nanomedicine, and neuroimmunology meet; experimental disease-model results are presented as research rather than evidence of a broadly available cure.