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Matt Koci Research Group

North Carolina State UniversityMore labs at North Carolina State University ↗

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How does the gut immune system distinguish helpful microbes from pathogens and build resistance to infection? The group investigates cellular and molecular aspects of immune responses, including how animals recognize, respond to and eliminate infectious organisms. One research direction examines innate immune responses involved in astrovirus-associated intestinal disease and its resolution in turkey poults and humans. Another studies how inherited variation in innate immune genes changes susceptibility or resistance to infection. The lab also examines relationships between intestinal microbes, gut physiology and mucosal immunity to understand their contribution to animal health.

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VirologyInnate immunityGut microbiomeHost-pathogen interactionsAstrovirus

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