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April Kloxin creates synthetic materials that let researchers change a cell’s surroundings while watching its response. Her group designs tissue-mimicking hydrogels whose properties can be altered at selected locations and times using triggers such as light or enzymes. These dynamic environments support three-dimensional cell culture, studies of disease progression, therapeutic delivery, and regenerative medicine. By controlling mechanical and biochemical cues, the research investigates how environments shape cell behavior. The work connects biomaterial chemistry with biological questions about tissue repair, differentiation, and disease mechanisms.
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